{"id":4235,"date":"2020-12-29T22:46:21","date_gmt":"2020-12-29T21:46:21","guid":{"rendered":"https:\/\/f101g.org\/gems-what-is-the-gems-project\/"},"modified":"2020-12-29T22:46:21","modified_gmt":"2020-12-29T21:46:21","slug":"gems-what-is-the-gems-project","status":"publish","type":"post","link":"https:\/\/f101g.org\/en\/gems-what-is-the-gems-project\/","title":{"rendered":"GEMS | What is the GEMS project?"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>GEMS stands for &#8221;&nbsp;<em>Genome-wide Epistasis for cardiovascular severity in Marfan Study<\/em> &#8220;<\/strong>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-1372 size-medium\" style=\"text-align: justify;\" src=\"https:\/\/f101g.org\/wp-content\/uploads\/2020\/12\/20190220-101-GENOMES-MARFAN-Circos.jpg\" alt=\"\" width=\"300\" height=\"261\"><\/p>\n<p style=\"text-align: justify;\">The aim of GEMS is to <strong>identify protective modifier genes<\/strong> (= epistatic genes) within the whole human genome capable of explaining the variability of cardiovascular damage found in people with Marfan syndrome. Such a discovery would open up new therapeutic avenues that would replicate the protective effects identified to prevent cardiovascular accidents.<\/p>\n<p style=\"text-align: justify;\"><strong>This research is at the heart of the 101 Genomes Foundation<\/strong>. It is led by Professor Bart Loeys and the entire scientific committee of the 101 Marfan Genomes Project.<\/p>\n<p style=\"text-align: justify;\">At the ABSM 20th Anniversary Gala, Professor Bart Loeys presented the GEMS project during his speech entitled <a href=\"https:\/\/f101g.org\/une-evocation-de-la-recherche-en-cours-et-perspectives-futures-par-le-professeur-bart-loeys\/\"><br \/>\n  <strong><em>&#8220;<\/em>&nbsp;<em> GEMS<em>-An overview of current research<\/em>&#8230;&#8221;<\/em><br \/>\n<\/strong>.<\/a> This presentation and its support are available on the F101G website.<\/p>\n<p style=\"text-align: right;\"><strong>Ludivine and Romain<\/strong><\/p>\n<p>&nbsp;<\/p>\n<a href=\"https:\/\/f101g.org\/wp-content\/uploads\/2019\/10\/20191005-04-LOEYS-Final_Loeys_Marfan-ABSM.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\" data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">20191005 04 LOEYS Final_Loeys_Marfan ABSM<\/a>\n<p>&nbsp;<\/p>\n<p>[embedyt]  https:\/\/www.youtube.com\/watch?v=zRHdEEitiQI[\/embedyt]<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>GEMS stands for &#8221;&nbsp;Genome-wide Epistasis for cardiovascular severity in Marfan Study &#8220;. The aim of GEMS is to identify protective &hellip;<\/p>\n","protected":false},"author":3,"featured_media":3235,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[61],"tags":[],"class_list":["post-4235","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gems-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>GEMS | What is the GEMS project? - 101 Genomes Foundation - Genomics for Rare Diseases<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/f101g.org\/en\/gems-what-is-the-gems-project\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GEMS | What is the GEMS project? - 101 Genomes Foundation - Genomics for Rare Diseases\" \/>\n<meta property=\"og:description\" content=\"GEMS stands for &#8221;&nbsp;Genome-wide Epistasis for cardiovascular severity in Marfan Study &#8220;. 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